Tumor microenvironment analysis in NSCLC…
Introduction In the field of cancer research, many advancements have been made over the last decade through studies of the…
InnoQuant
Fluorescence whole-slide scanner
Image Gallery
Cancer tissue micro environment analysis
Histo morphometry
Micro environment array
Plant phenotyping
IF cell Screening
Biomarker spatial analysis
TMA biomarker validation
Tissue immunophenotyping
What to expect from InnoQuant’s unique wholde slide scanning technology?
Reproductible results
- Inherent hardware calibration Argolight®validation slide
- 7 emission filters to detect the most specific signal and reduce fluorescence crosstalk
Multiplexing capabilities
- 4 independent PMT
- 7 positions filter wheel per channel
Throughput capabilities
- 24-slide autoloader
- Multiple ROI per slide
- Custom settings for each slide
Homogeneous image
- Point by point scanning
- Full-width line scanning
- No tiling, no stiching
Quick time to results
- 4 colors simultaneously scanned
- 17 min for a 3.2 cm2area
- No post-processing
- Focus without user intervention
Quantitative data
- Spatial signal homogeneity
- Up to 16-bit TIFF images
Remotely operable
- Server based installation
- User-friendly software interface
Easy image handling
- Non-proprietary format
- Multi-resolution TIFF
- Compatible with multiple analysis softwares
Applications
Plant Autofluorescence
Plants are ideal organisms in the studying of cell functions and organization. In comparison to an animal model, plants are…
Cell Immunofluorescence
Fluorescence immunostaining techniques on cultured cells or individual cells help to follow the protein expression and activity changes by targeting…
Tissue Immunofluorescence
Using fluorescence-labelled antibodies against specific antigens make it possible to highlight the presence of a molecule of interest directly within…
Infectiology
Protein detection by fluorescence-labelled antibodies on tissue sections is a widely used technique for the biomarker screening in complex diseases…
User friendly software interface: get your fluorescence images with minimal training
Aware of the complex intricacies of fluorescence imaging and parameters setting, Innopsys chose to design an easy-to-use, optimized software interface. No intense training is required to be able to obtain the best possible fluorescence images. The parameters can be adjusted during the scan to observe their impact in real-time.
Enhance multiplexing options with our customizable filter wheels
InnoQuant’s excitation and emission technical specifications are suited for your needs in fluorescence imaging
InnoQuant features 4 laser excitation wavelengths of 375 nm, 488 nm, 561 nm, and 640 nm, each associated with a 7-position emission filter wheel and a corresponding PMT. The filter wheel enhances the multiplexing capabilities of InnoQuant to obtain high resolution fluorescence images suited to your application. InnoQuant is equipped with 4 default emission filters (one for each channel): 440/40 for the 375 nm channel, 513/17 for the 488 nm channel, XXX for the 561 nm channel, and XXXX for the 640 nm.
Related documents: explore Innoquant’s whole slide imaging capabilities
InnoQuant Technical Specifications
| LASER EXCITATION WAVELENGTH | 375 nm | 488 nm | 561 nm | 640 nm |
| EMISSION FILTERS | FF01-440/40 | FF01-513/17 | FF01-593/40 | FF01-680/42 |
| For customization: 6 additional position filters for each PMT | ||||
| COMPATIBLE FLUOROPHORES* | DAPI Alexa Fluor 350 Hoechst DyLight 350 | FITC Alexa Fluor 488 Cy2 DyLight 488 | TRITC Alexa Fluor 561 Cy3 DyLight 594 | DRAQ 5 Alexa Fluor 647 Cy5 DyLight 650 |
| DETECTION TYPE | 4 independent photomultipliers (PMT) | |||
| PMT GAIN | Linear from 0.01 to 100% | |||
| ACQUISITION MODE | 4-color simultaneous acquisition | |||
| FOCUS MODE | 3 different focus options (Fully automated in-content focus; Real-time autofocus; Fixed focus) |
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| SLIDE SIZE | Compatible with standard microscope slides: 26 x 76 mm / 1 x 3 inch Maximal thickness 1.8 mm / 0.07 inch |
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| LOADER CAPACITY | Single slide or 24 slide-autoloader | |||
| SCANNING AREA | Adjustable up to 26 x 76 mm / 1 x 3 inch | |||
| SCANNING TIME | 17 min for a scan area of 18 x 18 mm / 0.70 x 0.70 inch at pixel size 0.5 μm | |||
| PIXEL SIZE | From 0.5 to 40 μm | |||
| IMAGE FORMAT | Non-proprietary image format (multi-resolution TIFF) | |||
| BARCODE READER | Automatic barcode reading | |||
| POWER SUPPLY | ~ 100-240VAC, 1.2 A, 50-60 Hz | |||
| DIMENSIONS (mm) & WEIGHT (kg) | (W) 429 x (D) 696 x (H) 521 ; 52 kg | |||
| DIMENSIONS (inch) & WEIGHT (lbs) | (W) 16.88 x (D) 27.40 x (H) 20.51 ; 114.64 lbs | |||